The cohort included: Five women Mean age: 57.4 years (range: 3777 years) Among the nine cases, the researchers identified: Seven patients with nonarteritic ischemic anterior optic neuropathy (NAION) One patient with bilateral papillitis One patient with paracentral acute middle maculopathy (PAMM) Some patients presented with unusual characteristics, including: Sequential ischemic optic neuropathy Bilateral disc swelling at initial presentation Progressive vision loss The authors emphasize that the study does not confirm a causal relationship between semaglutide, tirzepatide, and these ophthalmic conditions
Treatment history: Previous responses to other weight management or diabetes medications
Some people experience mild symptoms such as localised redness, widespread itching, tenderness, or irritation around the injection site
GLP1-RAs, developed to treat diabetes and obesity, have shown hepatoprotective and anti-inflammatory effects in preclinical models of AH [128-131]
The pharmacology of GIP/GLP-1/Glucagon receptor co-agonists
Pantothenic Acid (from Calcium Pantothenate) 10 mg