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Each 1g/day increase in isoleucine, leucine, and valine intake increased high LDL cholesterolemia risk by 30%, 11%, and 16%, respectively (121)

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Gipr hypo-KO also abolishes the synergistic effect of a GIPR antagonist when combined with liraglutidean effect that is not mediated by nucleus tractus solitarius preproglucagon neurons

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Role of Ghrelin in Obesity Control Ghrelin is an endogenous ligand of the growth hormone secretagogue receptor (GHSR)