A key point of our study is our finding of a reduction of glutathione in NTG patients, suggesting that excessive oxidative stress may contribute to optic nerve damage and RGC loss independently of high IOP in glaucoma
So, something else was going on there
If youre not currently exercising, Hyman recommends starting slow and building up to 30 minutes a day of vigorous aerobic exercise like walking, running, or others sports
Glutathione is the rate-limiting factor in this equation
Detoxification : It facilitates the elimination of toxins and heavy metals from the body, which is vital for maintaining a healthy liver and an efficient detoxification system, thus protecting the body from the accumulation of harmful substances
KEAP1/NRF2 mutant cells are protected against cysteine-starvation induced ferroptosis due to elevated GCLC expression and limited glutamate accumulation, and dual targeting of cystine import and GCLC activity can overcome the resistance of NRF2 active cells to ferroptosis (Kang et al., Cell Metab 2021)
