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Alterations in mitochondrial functions such as oxidative phosphorylation (OXPHOS) and membrane polarity, which enhance oxidative stress and apoptosis, may precede the development of depressive symptoms [84, 88, 89]

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In recent years, the introduction of emerging algorithms like graph neural networks (GNN) has further enhanced the research capabilities of NP

Interventions affecting TMAO and SCFAs, such as butyrate, correlate with improved cardiovascular profiles