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Studied in incretin pathway models involving glucose-associated signaling, satiety-pathway biology, and metabolic response systems

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Mitochondrial 12S rRNA encoding a 16-amino-acid peptide named MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) that regulates insulin sensitivity and metabolic homeostasis

GLP-1 agonists as weight-loss medications The use of GLP-1 medications to treat diabetes eventually revealed an additional metabolic benefit: weight loss