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But anything longer than a few weeks could start to pose a problem

In nonindustry-sponsored analyses, net costs per quality-adjusted life year have ranged from $237,000 to $483,000, 83 with low cost-effectiveness related to plateauing of weight benefits but continued high costs of treatment, as well as weight regain following any cessation of use

Tm hiu v Quy trnh bin tp hiu r hn cch chng ti m bo ni dung lun chnh xc, minh bch v tin cy

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Human trials are ongoing, but even modest effects in opioid use disorder could be clinically meaningful given the favorable safety profile of GLP-1 drugs compared with existing treatments

107 , e825e835 (2022)