chenodeoxycholic acid comprises 35%, while cholic acid constitutes 37.5% (182, 183)
When additional weight loss plateaus or weight regain occurs years post-surgery, GLP-1 receptor agonists like tirzepatide present a new optionbut their use in this population requires careful consideration of altered physiology, medication absorption, and personalized dosing strategies
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Adjust the treatment plan if needed
EMA decision P/0336/2024: paediatric investigation plan for retatrutide