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For one, it makes a robust clinical trial logistically tricky, said Christopher Milne, past director of research at the Tufts Center for the Study of Drug Development

The growing prevalence of metabolic syndrome has only exacerbated these challenges as our transplant recipients either have pre-existing diabetes mellitus and/or CKD or develop these conditions post-transplantation

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Similarly, the Step-1 extension trial featuring 327 participants treated with semaglutide for 68 weeks produced similar results

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Morning administration often works well for many users, as it helps control appetite throughout the day