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A broad spectrum of GLP-1 RAs has been approved by the Federal Drug Administration (FDA) to treat T2DM, including exenatide, liraglutide, albiglutide, dulaglutide, lixisenatide, and semaglutide (Liu, et al., 2022)

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Front Immunol 16:1563303 Du H, Xu T, Yu S, Wu S, Zhang J (2025) Mitochondrial metabolism and cancer therapeutic innovation

The authors hypothesized that the physiological significance of DHAR activity depends on the ascorbate pool size and that DHARs are required only at high levels of ascorbate

Researchers are expected to follow institutional biosafety rules, animal-care guidelines, and local regulations when working with KLOW, just as they would with any other unapproved laboratory reagent