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Glutathione supplementation alters the redox environment of the intestinal lumen, favoring species that thrive in low-oxidative-stress conditions
Crucially, this worked at extremely low concentrations picomolar to nanomolar suggesting high biological potency
191196, Dec
doi: 10.3389/fcimb.2025.1714998 Received 28 September 2025 Revised 11 November 2025 Accepted 17 November 2025 Published 01 December 2025 Volume 15 - 2025 Edited by Manmohan Kumar, The University of Texas Health Science Center at San Antonio, United States Reviewed by Yangyang He, The University of Texas Health Science Center at San Antonio, United States Raj Priya, University Bloomington, United States Updates Copyright 2025 Yang, Zeng, Liu and Huang
The other thing that sets it apart from most treatments is how it's delivered
GSOH can also react with other thiols, such as cysteine residues, forming mixed disulfides (e.g., cystein-glutathione disulfide) (Gupta and Carroll, 2014)
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