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They can improve the appearance of hyperpigmentation and other forms of skin discoloration to leave skin looking healthier
tirzepatide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2
Many describe it as the first time in their lives that they felt genuinely neutral about food able to leave half a meal without effort, uninterested in snacking, and free from the mental chatter around eating that had defined their relationship with food for years
57 Furthermore, a subsequent prespecified analysis of the trial examined the effects of semaglutide in patients with and without history of HF at enrolment, with a significant reduction in MACE in patients with HFrEF and HFpEF and a 21% and 25% reduction in the HF composite endpoint, respectively
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Raparelli, V., et al
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