glp-1 sglt2 Common systemic effects of either inhibitors or GLP-1R agonists GLP-1 Receptor Agonists | New

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted by intestinal L cells in response to dietary intake

A new positive for junior Springbok prop Kai Pratt, SAIDS rejecting the "witch hunt" framing, and Ross digs into the numbers: testing down more than six-fold in a decade, South Africa accounting for one in five rugby doping cases worldwide, and an anti-doping body whose budget has flatlined

More serious risks include: Pancreatitis Gallbladder issues Risk of thyroid tumors (observed in rodent studies) Patients must weigh these risks carefully, especially when using the medication off-label

Phase 3 trials are ongoing, and no regulatory submission has yet been made to the MHRA or EMA

Hypoglycemia: The risk is less with GLP-1 RAs

If anaphylaxis or severe allergic reaction is suspected, the medication should be discontinued immediately