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On evolving topics, studies from pre-print journals may be sourced

People with heart conditions or hypertension People with known heart disease, hypertension, arrhythmia, or a family history of sudden cardiac death should limit or avoid high-caffeine energy drinks (S5)

Medication such as birth control pills, to keep ovarian cysts from recurring

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Numerous toxicity studies have been done to assess the safety of MSM and doses up to 4,845.6 mg per day (4.8 grams) appear to be safe ( However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhea

You must regularly consume plenty of water throughout the day