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4 Inflammatory immune cells including dendritic cells, macrophages, lymphocyte subsets (especially TH17 cells), and B cells infiltrate into the synovial structure and cause more inflammation and tissue destruction

ATCC CCL-185) cell lines were cultured at 37 C, 5% CO 2 in DMEM with 4.5 g/l of glucose, 1% penicillin/streptomycin (P/S) and 10% of heat-inactivated fetal bovine serum (FBS) (Gibco BRL, Gaithersburg, Md.)

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For teams that want to explore oral delivery, BPC capsules receive similar treatment, with discussion of how to differentiate capsule-based protocols from injectable or in-vitro formats

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