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Glutathione (GSH) is the most preferred co-factor reducing substrate in mammalian GPX enzymes, although GPX4 has the unique ability to utilize other protein thiols in addition to GSH [51]

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[2] Treated animals showed progressive recovery of tail motor function, absence of autotomy, and resolution of spasticity, alongside electromyographic changes and a microscopic profile in which the vacuolization, white-matter axon loss, gray-matter edema, and motoneuron loss typical of the injury were attenuated