Doctors here (state of Maryland, USA) are required to follow the standard of carenot just for PA, but for any condition that has an established standard of care
An IM injection delivers medicine directly into a muscle rather than under the skin, allowing faster absorption and avoiding some of the delays or limits of oral or subcutaneous routes
Concomitant use with drugs that require acidic pH for absorption may reduce their efficacy
Some protocols begin with a brief intensive phase (for example, daily or alternate-day dosing) followed by a maintenance phase (for example, weekly to monthly), particularly for B12 deficiency
doi: 10.1055/s-0040-1718721 [PubMed] 33273175 Lee EQ
8 A case-control study that compared 25,956 patients who had vitamin B 12 deficiency with 184,199 control patients found a significantly increased risk of vitamin B 12 deficiency in patients who had taken proton pump inhibitors (odds ratio = 1.65) or histamine H 2 blockers (odds ratio = 1.25) for at least two years