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Under these conditions, we measured a decrease in insulin secretion in response to exendin-4 versus vehicle conditions, primarily due to elevated basal secretion levels at 11 mM glucose (Figure 1E, F), confirming that increased cholesterol levels reduce the GLP-1R glucoregulatory potential by decreasing its capacity to potentiate islet insulin secretion

When the results of the study came back, it was very clear that exercise and education was the winner

Effect of Feeding an Iodine-Restricted Diet in Cats with Spontaneous Hyperthyroidism

We like to think of it as giving your gut its rhythm back

GLP-1 medications don't fail because of chemistry

Researchers easily obtain GLP-1 prescriptions online, clinician interaction lower than expected Yale University researchers were able to easily obtain GLP-1 prescriptions online using fake patient profiles, in some instances receiving prescriptions in less than five minutes and with minimal interaction with clinicians